According to the German Helmholtz Research Center's official website on the 9th, researchers from the Center's Dresden Rosendorf and Paderborn University made breakthroughs in the development of genetic material circuits: for the first time, they added gold-plated nanoparticles. Current is detected in single-stranded DNA self-assembled nanowires. Related research was published in the scientific journal Langmuir. In recent years, the important components of computer chips have been reduced to 14 nm, but the traditional process is always cut from the larger size to the desired structure. This "top-down" approach has now reached the physical limit, the smaller the size The harder it is. Researchers have been looking for alternative methods, and self-assembly of complex components with atoms and molecules is one of them.
This self-assembly is like origami technology, which is a "bottom-up" approach that subverts traditional processes. Small molecules self-assemble into larger complex structures that do not require shear-shrinking. Artur Aeb, who participated in the study, explained that this DNA nanowire is formed by the use of a longer single-stranded DNA and several shorter DNA fragments by base pairing. The smallest computer chip assembly available today is much smaller and can be used to make very small circuits.
However, DNA wires have long been faced with a major problem: they cannot conduct currents very well. Ebb and colleagues overcome this problem by bonding gold-plated nanoparticles to DNA wires and then using electron beam lithography to connect each nanowire through the electrodes. “Connecting the larger electrode to the DNA structure solves the technical problem that has long been plagued. Now for the first time we can accurately detect the amount of charge flowing through the DNA wire,†explains Ebou.
Although the researchers actually detected current conduction, the magnitude of the current was related to the ambient temperature. At room temperature, the nanowires have normal electrical conductivity. Even if the wires are not tightly integrated, electrons will jump from one gold particle to another to form an electrical current.
Ebb pointed out that currents can only be measured current, because the transmission distance is too short, the most advanced microscope can not capture. Next, they will continue to improve, adding conductive polymer materials to the gold particles, optimizing the metallization process, and replacing gold particles with more cost-effective metals.
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